You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air

https://telegra.ph/Why-San-Diegos-Climate-Makes-Roof-Rat-Proofing-a-Year-Round-Job-10-08

You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air and raise the risk of exposure to rodent-borne diseases.